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Flecainide, in addition to significant sodium channel blocking activity, has mild I Kr blocking effects but is not generally associated with significant QT prolongation.

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Searches were undertaken according to the parameters stipulated within the Guidelines Manual 2012 (see the "Availability of Companion Documents" field).

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AFL, three fixed dose levels of sotalol hydrochloride tablets (AF) (80 mg, 120 mg and 160 mg) twice daily and placebo were compared in 253 patients.

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Perform an electrocardiogram (ECG) in all people, whether symptomatic or not, in whom AF is suspected because an irregular pulse has been detected.

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In patients with AFIB and sinus node dysfunction, the risk of Torsade de Pointes with sotalol (AF) therapy is increased, especially after cardioversion.

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Pretreatment before PCI: oral prasugrel 60 mg is recommended.

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Fluid retention, which may lead to or exacerbate heart failure, can occur with concomitant use of thiazolidinediones (TZDs) with insulin.

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In patients who experience an exacerbation of angina following discontinuation of beta-blocker therapy, the medication should generally be reinstituted, at least temporarily, along with other clinically appropriate measures.

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Antiarrhythmic drugs have traditionally been the mainstays of treatment for clinically stable patients with VT.

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Thus, according to Abraham and his colleagues, the Wolff-Chaikoff effect is of no clinical significance.

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Another case report described mirtazapine as inducing in a -treated patient, likely due to occupancy of α 2 autoreceptors by mirtazapine limiting the efficacy of concurrent clonidine therapy.

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It is difficult to evaluate long-term antiarrhythmic therapy for patients with atrial flutter because most studies combine patients with AF and atrial flutter without specifying the results for each arrhythmia.

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Type II atrial flutter interruption with transesophageal pacing: use of propafenone and possible change of the substrate.

Do not use documentation that is dated prior to arrival or documentation which refers to the pre-arrival time period (e.

In all children, individualization of dosage is required.

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Yohimbine is marketed for treatment of sexual disorders and exhaustion.

This medication does not have an FDA approved indication for use in animals, but it is a common and acceptable practice for veterinarians to prescribe this human medication for use in animals.

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Holter monitoring to predict antiarrhythmic-drug efficacy for ventricular tachyarrhythmias.

Because implantable cardioverter-defibrillators (ICDs) are more effective than amiodarone in reducing mortality in high-risk patients with previous myocardial infarction, primary treatment should be an ICD.

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This question of whether the β-blockers exhibit a class effect regarding cardioprotection has been addressed in the past by Hjalmarson.

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With its newly understood properties of 5-HT 2C inverse agonism, it is being investigated and shown to lower drug seeking behaviour, and the rewarding effects of substances such as methamphetamine in various human and animal studies.

The experience with propafenone is even more limited, although no adverse effects to the fetus have been reported when it is taken during the third trimester.

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Salt is iodized using potassium or sodium iodide.

See Appendix L, Cost-effectiveness of stroke prevention strategies in patients with atrial fibrillation (AF), in the full version of the guideline document.

The AMA disclaims responsibility for any consequences or liability attributable to or related to any use, nonuse or interpretation of information contained in this product.

Even with high-dose rapid infusions, all 3 agents are associated with a poor overall reversion rate within 12 hours.

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We had it during the Third Reich and it took quite a lot of government campaigning to bring back mass iodization, a public relations campaign to convince people that iodine is healthy and has no dangers at all.

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Alternatively, tricuspid regurgitation and a large ASD can cause cyanosis and hemodynamic compromise that may be exacerbated by arrhythmias.

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The expected rates of sustained sinus rhythm at one year were 60 percent in the amiodarone group, 50 percent in the sotalol group, and 35 percent in the placebo group.

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